Course Contents (Industrial Biotechnology)

COURSE CONTENTS

 

IBT 601 Fundamentals of Industrial Biotechnology (3-0)3 ECTS 9

Industrial Biotechnology is an interdisciplinary field in which various branches of science work together and people should master the principles of these branches of science. In this course, students are shown the applications of different disciplines in the field of industrial biotechnology, and the basics of these disciplines are introduced.

BTEC 510 Ethical Issues in Life Sciences (3-0)3 ECTS 9

The course, in accordance with its aims, examines and elaborates on ethical issues in life sciences with a special emphasis on the ethical, social and environmental implications of animal and plant biotechnology. On the one hand, it focuses on the ethical issues that are relevant to the internal conduct, i.e., philosophical, epistemological and methodological procedures, of life sciences; and, on the other hand, it examines the questions regarding the ethical conduct of the researcher in research design, data collection, the evaluation of data, and the presentation of the findings.

IBT 698 Research Seminar (0-2)NC ECTS 9

In this course, the student makes a literature survey on his/her thesis subject, compiles data, analyzes and reports the results and conveys them to the audience with an oral presentation.

IBT 600 PhD Thesis (0-1)NC ECTS 26

The student proposes an independent study, plans and performs experimental and/or theoretical work and prepares a PhD thesis on a research topic in the field of industrial biotechnology. The work is supervised by at least two faculty members, one main and one assistant counselor from different disciplines as advisors.

IBT 8XX Special Studies (8-0)NC ECTS 4

Graduate students study advanced topics under the guidance of their advisor.

Elective Courses

IBT 615 Bioprocess Technology (3-0)3 ECTS 9

Production of bio-based products is an interdisciplinary process, in which basic sciences and engineering sciences are utilized together. In those processes, the basics of several disciplines, such as microbiology, biochemistry, and chemical engineering are applied. In this course, industrial processes that utilize enzymes, microorganisms, and mammalian cells are examined and the basic information necessary for their design, operation, and analysis are given. Fluid mechanics, heat, and mass transfer concepts are introduced for the analysis of processes such as mixing, heating-cooling, and aeration in bioreactors.

IBT 620 Enzymes in Biotechnology (3-0)3 ECTS 9

Introduction to Enzymes: History and development of enzymology, enzymes and their properties as biocatalysts, enzyme reaction mechanism, enzyme activity and factors affecting enzyme catalyzed reaction, control of enzyme activity,

Use and application of enzymes: Enzyme immobilization and immobilization methods, economic importance of enzymes and their usage in industry, various biotechnological applications of enzymes

IBT 630 Lignocellulose Biotechnology (3-0)3 ECTS 9

The cost and sustainability of feedstocks to be used in the production of bio-based products is a major concern. Biomass, which is also described as the third-generation raw material and emerged as the waste of agricultural, food and forestry activities, is the feedstock with potential for industrial production. In this course, the technologies used for the utilization lignocellulosic plant biomass in industrial applications are introduced; pretreatments applied to biomass, hydrolytic enzymes and microorganisms used are mentioned; Examples of the bioprocesses that valorize the cellulose, hemicellulose and lignin that make up lignocellulose are given.

IBT 635 Introduction to Synthetic Biology (3-0)3 ECTS 9

Synthetic biology is a multidisciplinary field of research aimed at creating new biological parts, devices and systems, or redesigning systems found in nature. This course introduces synthetic biology and provides students with a basic concept necessary to understand this field. In this course, the creation of artificial gene networks will be explained using the information obtained by examining biological systems and the principles used by organisms to perform cellular tasks. This course includes DNA chemistry and applications, protein structure and purification, gene engineering and metabolic engineering, biological circuits and other applications of synthetic biology.

IBT 640 Immobilization in Biotechnology (3-0)3 ECTS 9

In the course content, after explaining the reason and importance of immobilization in biotechnology, methods used, carriers used, physical and chemical characterization methods will be discussed in detail. Immobilization methods will be compared. The immobilization methods used in biotechnology will be explained with examples in different fields of biotechnology.

IBT 645 Industrial Bioseparations (3-0)3 ECTS 9

Bioseparation is a technique by which the products of fermentations or biotransformations are recovered for subsequent use. Industrial bioseparations offers comprehensive coverage of bioseparations including all recovery and purification operations for commercially important biomacromolecules. This course refers to the systematic study of the scientific and engineering principles utilized for the large-scale purification of biological products, offers a balance between the fundamentals of bioseparations processing and the practical applications in industry today. Starting from laboratory scale experiments, scale up parameters as well as commonly used operating conditions and applications to industrial scale are covered.

IBT 650 Probiotics and Bioactive Compounds (3-0)3 ECTS 9

This course offers a novel focus on probiotics and synbiotics to help designing functional food and nutraceutical products to prevent various diseases and improve health. The efficiency of probiotics for infections, gastroenterology, endocrinology, cardiology, neurology, urology etc. is discussed together with evaluation of research e.g. gut-brain axis.  Modifications with bioflavonoids and prebiotic fibrous materials were also defined to support the actions of  probiotic microorganisms. A major emphasis is placed on the health-promoting activities and bioactive compounds of probiotic bacteria in the context of this course.

IBT 655 Fungal Biotechnology (3-0)3 ECTS 9

Fungal taxonomy, Fungal diversity, Classification of fungi, Fungal cell structures, physiology and growth, Fungal ecology, Interactions between fungi and other microorganisms, Chemical identification of fungi, Metabolite profiling and metabolomics, Molecular methods for detection and identification of fungi, Mycotoxigenic fungi and mycotoxins, Fungal spoilage of food and feed, Phytopathogenic fungi, Entomopathogenic fungi, Plant growth promoter and disease suppressor fungi, Fungal primary and secondary metabolites, Fungi in food industry, Antifungal food additives, Biotechnological approaches in plant protection, Mycoherbicides, Biodegradation by fungi, Bioremediation by fungi, Bioconversion of industrial wastes by fungi

IBT 660 Industrial Applications of Algal Biotechnology (3-0)3 ECTS 9

Microalgae are single cellular photosynthetic microorganisms that are expected by many to play an important role for the solution for most pressing industrial problems of the 21th century such as sustainable production of energy and food. Within this context, this course aims to answer questions such as (i) why algae are considered unique as a biobased source, (ii) how they are used as production platform for a range of products, (iii) what their limitations are, (iv) how algae cultivation systems can be designed, (v) what the current industrial uses for algal biotechnology are, and (vi) what may be their future industrial applications.

BTEC 580 Special Topics in Biotechnology (3-0)3 ECTS 9

Contents vary according to interests of students and instructors in charge. Contents may include advances in modern biotechnology, plant and animal cell cultures, modeling and simulation of bioreactors and metabolite production. Preparation of a literature review paper on the student’s interest or research area will be required at the end of this course.